Onkológia 4/2014

Metastatic prostate cancer: principles of hormonal treatment

Hormonal manipulation in prostate cancer therapy is known for more than a century and it still persists as a treatment of choice in presence of distante metastases. Recently with the wide use of PSA (prostatic specific antigen) evaluation in males above 50 years a dramatic decrease of metastatic disease at diagnosis was observed. Author presents the essential principles of hormone therapy considering prognostic factors of not only the disease, but also the patient himself.

Keywords: prostate cancer, metastatic disease, hormone therapy.