Onkológia 5/2016

Therapeutical management in high-grade gliomas

The paper analyses treatment procedures for malignant gliomas based on oncologic studies. It discusses the benefits of the new 2016 WHO classification, which complemented traditional classification principles based on histological criteria with molecular markers. The identification of genetic and epigenetic profiles in different gliomas has adjusted the glioma classification and improved prediction of treatment response.

Keywords: high-grade gliomas, radiotherapy, chemotherapy, molecular markers, WHO classification 2016