Onkológia 4/2016

Current possibilities of the treatment of multiresistant nosocomial infections

Growing antimicrobial resistance to used antibiotics leads to the problem in deciding about the type of antibiotic both in empiric and targeted treatment of patients, especially oncologic and haematologic patients. One can observe the renewed use of older antibiotics, which are often the only possibilities of treatment – fosfomycin, colistin/polymyxin B, tigecyclin, daptomycin. There is not enough information about use of these antibiotics especially in haematologic patients, where is the presumption of drug interactions. Therefor the Expert Group at the ECIL-4 meeting established the working guidelines for the use of antibiotics against multiresistant pathogenes.

Keywords: resistance, antibiotics, gram-positive bacteria, gram-negative bacteria, hematologic