Onkológia 3/2010
Risk of development of germinal tumours in patients with gonad dysgenesis
Gonadal dysgenesis is a part of congenital anomalies known as disorders of sex development. Patients with specific variants of DSD have an elevated risk for the development of various types of germ cell tumors. It is very difficult to determinate the actual risk for malignant transformation in individual DSD patient because of confusing terminology and classification of different types of DSD.
Keywords: disorders of sexual differentiation, gonadal dysgenesis, primary amenorrhea, causes of amenorrhea, risk of cancor.
