Onkológia 1/2006

PROSTATE CANCER – EPIDEMIOLOGY, ETIOLOGY, DIAGNOSTICS, CLINICAL SYMTOMPHS, SCREENING

Prostate cancer presents a real important medical and social problem at present. It is one of the most common malignancy in males. In global point of view it means permanent incidence increase of this disease. Despite improvement of prostate cancer diagnosis and complex treatment mortality does not decreased significantly. Knowledge of etiological factors are relatively limited. Important factors are: genetic disposition, age, life style, race, positive familial history, circulated androgens. Diagnostics is well known, based on routine clinical methods: digital rectal examination, measurement of PSA a transrectal ultrasound. Benefit of prostate cancer screening is until now unclear, controversial.

Keywords: prostate cancer, epidemiology, etiology, diagnostics, screening.