Onkológia 3/2006

INCIDENCE AND CURABILITY OF TUMORS IN CHILDHOOD IN SLOVAKIA

Annual incidence of cancer in Slovak Republic for children 0 − 14 years old in 1991 – 2002 was 115,2 – 143 per million and for adolescents 15 – 19 years old 156 – 196 per million, in which mild increase was observed. Most often malignancies in children have been acute lymphoblastic leukemia and tumors of central nervous system. for children 0 – 4 years old have been characteristic also embryonal tumors (neuroblastoma, wilms´ tumor, retinoblastoma). In older than 10 years incidence of Hodgkins´ lymphoma, osteosarcoma and carcinomas has been increasing. All children and adolescents 0 – 18 years have been treated exclusively in the last 10 years in three pediatric oncological centers. The survival significantly improved in last 10 years. Overall 4years survival has been 76 % in years 2000 – 2003 in comparison with 5years survival 63 % in 1990 – 1994. More than 75 % survival was achieved in acute lymphoblastic leukemia, Hodgkins´ and nonHodgkins ´ lymphomas, retinoblastoma, wilms´ tumor, germinal cell tumors and softtissue sarcomas. The worst survival was observed in acute nonlymphoblastic leukemia (56 %) and liver tumors (41 %).

Keywords: malignancies in children, incidence, survival, treatment results.