Onkológia 4/2016

Immunotherapy for lung cancer

Lung cancer is among the tumours which are most studied as the targets of immune-based therapies in oncology. Currently, there are three main categories of immunotherapeutic drugs used for lung cancer - monoclonal antibodies, therapeutic vaccines, and immune checkpoint inhibitors. In this review, the basic information about the mechanism of action, results of the key clinical trials, and the information about the recently opened new trials with immunotherapies for lung cancer are discussed. Recent approvals of first drugs from the group of immunotherapies confirm that immunotherapy is becoming a new modality of lung cancer treatment.

Keywords: lung cancer, immunotherapy, monoclonal antibodies, vaccines, immune checkpoint inhibitors