Onkológia 1/2011

Lymphoma biologic therapy

The term of biological therapy is not exactly defined, but from this group of therapeutics are currently in the treatment of malignant lymphomas used conjugated and unconjugated monoclonal antibodies and to lesser extent interferon-alpha. Introduction of rituximab into treatment protocols of the patients with B-cell lymphomas has been the most important step in clinical practice during previous decade. There is currently ongoing substantial number of clinical trials studying different drugs belonging to the designation biological therapy. Some of them can become standard part of our treatment schemes in the near future.

Keywords: lymphoma, biological therapy, monoclonal antibodies, interferon-alpha, anti-idiotype vaccines.