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Onkológia 5/2009
Adjuvant therapy of prostate cancer
Outcomes of radical prostatectomy (RP) in high risk prostate cancer are suboptimal. Intensification of local therapy as well as early administration of systemic treatment adjuvant to RP is subject of clinical research. Results of randomised studies are presented. Improvement in overall survival has been reported in adjuvant radiotherapy (RT) in pT3 (extracapsular extension and seminal vesicles invasion) or positive resection margin (R1) and in adjuvant androgen deprivation therapy (ADT) in pN+ disease.
Keywords: prostate cancer, adjuvant radiotherapy, adjuvant androgen deprivation therapy, adjuvant chemotherapy
