Neurológia pre prax 2/2020

The pitfalls of treating rapidly evolving multiple sclerosis

In this case report of a young female patient with multiple sclerosis, we demonstrate three pitfalls of current treatment in patients with this condition: the issue of accurate diagnosis in ambiguous cases; the choice of appropriate immunomodulatory therapy in a previously untreated patient; and the safety of treatment and related prophylactic measures. The paper discusses selected sections of the current guidelines and demonstrates the advantages of interdisciplinary cooperation which, in this particular case, resulted in a personalized vaccination scheme for active immunization against the varicella-zoster virus.

Keywords: multiple sclerosis, immunomodulatory therapy, active immunization, fingolimod, varicella-zoster virus