Neurológia pre prax 6/2009

Treatment of choreatic dyskinesias

Choreatic dyskinesias are caused by the hetegenous dysfunctions of basal ganglia system. For clinical settings we have several options: antipsychotics (i. e. risperidone, tiapride), presynaptic dopamine depletors (tetrabenazine), GABAergics (clonazepam), antiglutamatergics (i. e. amantadine). Their intensity could be pharmacologically controlled, at least partially, however their causal curability is only seldom available.

Keywords: chorea, antipsychotics, clonazepam, amantadine, tetrabenazine, clinical studies.