Neurológia pre prax 6/2014

Pure akinesia with gait freezing

This article describes a relative „young“ and rare diagnosis on the field of movement disorders, known as pure akinesia or pure kinesia with gait freezing. The cardinal clinical feauture of the syndrome is akinesia and levodopa-resistant progressive freezing during walking, speaking and handwriting. Limb rigidity, oculoparesis and dementia are not present. Pathologically this syndrome shows changes typical for progressive supranuclear palsy, therefore pure akinesia is regarded as its clinical variant. The article presents a short clinical case of a patient reflecting a graduate conversion of seven years existing pure akinesia to the typical clinically and imaging signs of progressive supranuclear palsy.

Keywords: pure akinesia, pure akinesia with gait freezing, progressive supranuclear palsy, clinical case.