Neurológia pre prax 3/2014
Link atrophy and disability in multiple sclerosis
Brain and spinal cord atrophy in multiple sclerosis occurs due to neurodegeneration either demyelinated axons or their direct damage. The development of unconventional techniques of magnetic resonance imaging allows accurate assessment of global or regional atrophy that correlates with disability. Some of already registered drugs and others that are in the stage of clinical testing show a neuroprotective effect, affecting disability and therefore quality of life.
Keywords: multiple sclerosis, atrophy, pseudoatrophy, disability, neuroprotection.
