Progresivní paralýza – příčina neurokognitivní poruchy v mladém věku // SOLEN

Neurológia pre prax 1/2025

General paresis – the cause of neurocognitive disorder at a young age

The infectious disease syphilis is among the most common sexually transmitted diseases worldwide. Due to the neuroinvasiveness of the infecting treponemal strain, patients can encounter a wide variety of central nervous system involvement, which can occur during any stage of the disease. This article reviews the different stages of syphilis and neurosyphilis. In the form of case report of a young patient, we describe the late stage of syphilis as general paresis.

Keywords: syphilis, neurosyphilis, general paresis, neurocognitive disorder