Neurológia pre prax 4/2023

Progressive multifocal leukoencephalopathy as a primary opportunistic infection in a patient with AIDS

Progressive multifocal leukoencephalopathy is a rare demyelinating disorder of the central nervous system, which is found almost entirely in immunocompromised persons – mostly as late complication of HIV infection. We present a case report of rare situation, in which the diagnosis of PML preceded the diagnosis of long-lasting HIV infection. This patient was also the first patient with this diagnosis in Neurology department of The University Hospital Olomouc.

Keywords: leukoencephalopathy, progressive multifocal, HIV, acquired immunodeficiency syndrome, opportunistic infections