Neurológia pre prax 1/2017

A practical approach to sleep disorders in Parkinson’s disease and other synucleinopathies

Parkinson’s disease (PD), along with dementia with Lewy bodies (DLB) and multisystem atrophy (MSA), belongs to a pathologically defined group of diseases – synucleinopathies. They share not only a common pathological mechanism of origin, but also some clinical signs. Also frequent are sleep-wake disorders that further impair the quality of life of those affected as well as increase the overall morbidity and mortality.

Keywords: synucleinopathies, Parkinson’s disease, sleep disorders, REM sleep behaviour disorder, restless leg syndrome, excessive daytime sleepiness, insomnia