Neurológia pre prax 4/2015

Drug induced hepatopathy after fingolimod treatment

We report a case of 34-year-old man with multiple sclerosis with recurrent hepatopathy of toxicity grade 3 after Gilenya treatment in the first 6 months of our treatment. We must twice discontinue treatment with Gilenya due to hepatopathy. There was no episode of recurrent hepatopathy in the next 1,5 year. Our patient is clinically and radiologically stabilized.

Keywords: multiple sclerosis, drug induced hepatopathy, fingolimod.