Neurológia pre prax 3/2012

Parkinsonian syndromes: MSA and PSP as characteristic examples

Parkinsonian syndromes are a large and heterogeneous group of diseases. The classification of these diseases has been making a rapid progress and, due to advances in the field of molecular genetics in particular, it may be possible to distinguish new nosological entities in the future. Atypical parkinsonian syndromes can be divided into synucleinopathies and tauopathies, and other heredodegenerative diseases. Parkinsonian syndromes are most characteristically represented by multiple system atrophy (MSA) and progressive supranuclear palsy (PSP), with PSP being a type of tauopathy and MSA that of synucleinopathy. The present article provides general information on MSA and PSP.

Keywords: Parkinsonian syndromes, multiple system atrophy, progressive supranuclear palsy.