Neurológia pre prax 4/2019

A new era of multiple sclerosis treatment

Multiple sclerosis is very serious neurological disease. If not treated it causes severe disability of patients. New hope in treating MS arose in the nineties due to arrival of modern therapy. However only last couple decades have brought revolutionary changes in the treatment of this disease. Besides medicaments used continuously to affect the disease, we now have new specific therapeutic group called immune reconstitution therapy (IRT), which can induce long-term remission of the disease without continual treatment. New highly efficient therapy changes our views of goals in therapy of MS. Now our main goal is to achieve long-term remission of the disease, which is defined by the concept of No Evidence of Disease Activity (NEDA).

Keywords: multiple sclerosis,maintenance/escalation therapy, immune reconstitution therapy, no evidence of disease activity (NEDA)