Neurológia pre prax 6/2015

Cognitive impairment in multiple sclerosis

Multiple sclerosis is a chronic inflammatory disease which is characterized by infiltration of leukocytes into the central nervous system. This situation leads to the destruction of myelin and to the loss of axons and olidendrocytes. Cognitive dysfunction is present in all stages of multiple sclerosis. The impairment of information processing, memory and executive functions are typical findings. The NEDA-4 concept, testing of cognitive dysfunction and treatment are discussed.

Keywords: multiple sclerosis, NEDA-4, cognitive dysfunction.