Neurológia pre prax 6/2017

Cognition and multiple sclerosis

Multiple sclerosis (MS) is a chronic disease of the central nervous system leading primarily to motor and sensitive disability. Cognitive deficit is present in almost 70 % of patients with MS and is detectable even at the earliest stage of MS – in patients with clinically isolated syndrome (CIS). Because cognitive deficit has an important impact on a patients‘ quality of life, it is important to focus on their potential cognitive deficit in routine clinical practice. The aim of this review is to summarize new findings about cognitive deficit and neuropsychiatric symptoms in patients with MS and to describe how to manage cognitive deficit in patients with MS.

Keywords: multiple sclerosis, cognitive deficit, neuropsychological tests, Brief Internatiol Cognitive Assessment for Multiple Sclerosis, Minimal Assessment of Cognitive Function in Multiple Sclerosis, quality of life