Neurológia pre prax 4/2014

Ideopathic generalized epilepsies

Idiopathic generalized epilepsies (IGEs) constitute one-third of all epilepsies. They are genetically determinate in some epileptic syndromes the molecular-genetic etiopatogenesis is known. Clinical status is performed by age of onset of disorder, type of seizures (typical absences, myoclonic jerks, generalized tonic clonic seizures alone or in varying combinations) and characteristic EEG features. The article provides review of individual epileptic syndromes, their clinical status, diagnostic, therapy and prognosis with information about actually known molecular-genetic base of IGEs. Dividing of epileptic syndromes result from Proposal ILAE Task Force 2001.

Keywords: idiopathic generalized epilepsy, genetic, myoclonic epilepsy in infancy, epilepsy with febrile seizures, myoclonic-astatic seizures, myoclonic absences, childhood absences, juvenile absences, juvenile myoclonic epilepsy.