Neurológia pre prax 4/2023

Episodic ataxias

Episodic ataxias encompass a group of genetic or acquired conditions with episodic attacks of the cerebellar dysfunction, which may be associated with another various symptoms. Primary episodic ataxias are mainly young-onset. They are characterized by various frequency and duration of the attacks, and variable interictal features and response to acetazolamide (episodic ataxias type 1–9). Acquired episodic ataxias are usually late-onset and manifested by short lasting attacks and other features of underlying condition (multiple sclerosis and others). In this article, we provide a didactive overview and a brief diagnostic algorithm of episodic ataxias suitable for clinical praxis.

Keywords: episodic ataxias, EA1–9, primary episodic ataxia, acquired episodic ataxias, diagnostic algorithm