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Neurológia pre prax 3/2022
Elimination half‑life is not just a pharmacological profile
When choosing the optimal drug, we focus on several key characteristics of the drug. The drug pharmacokinetic profile is usually a less significant factor in this choice. The aim of the following article is to clearly explain why we should pay particular attention to the elimination half-life as an important pharmacokinetic parameter. We also want to point out its role in anti-seizure medication, for which the stability of plasma drug levels is essential.
Keywords: elimination half‑life, anti‑seizure medication, epilepsy
