Neurológia pre prax 3/2014

Long-term treatment with intraduodenal levodopa – case report of three patients

We present case reports of three patients with Parkinson‘s disease (PD) treated with intradudodenal levodopa – Duodopa. Duodopa enables continuous administration of dopaminergicv treatment indicated for patients with late motor complications. Administration of levodopa into the jejunal part of duodenum and easy dose setting leads to stable plasma levels of levodopa and an improvement of motor state of patients with PD. This invasive procedure plays an important role in therapy of late motor complications of PD.

Keywords: Parkinson´s disease, intraduodenal levodopa, case reports.