Neurológia pre prax 2/2017

What was hiding behind a migraine attack?

The case report presents a 60-year-old patient with a history of hypertension, ischaemic heart disease, hyperlipoproteinaemia, and long-standing migraine, who was admitted to our department for a prolonged migraine attack not responding to normally effective therapy. In the course of hospitalization, the patient developed diplopia and left oculomotor nerve lesion, with subsequent bilateral, progressive deterioration in vision. Laboratory and additional paraclinical testing revealed leptomeningeal carcinomatosis as well as a newly diagnosed gastric B-cell lymphoma.

Keywords: leptomeningeal carcinomatosis, paraneoplastic meningitis, oculomotor nerve lesion, lymphoma