Neurológia pre prax 2/2016

Chronic subdural haematoma associated with advanced malignant tumor

The study aims to present the case of prostate cancer patient with generalised metastatic skeletal involvement with sudden deterioration into comatose status and gradual development of bilateral mydriasis caused by bilateral non homogenous chronic subdural haematoma. After emergency bilateral frontal trephinations another surgery for residual subdural haematoma in parietal region was performed. Histological study of the resected outer membrane of the chronic subdural haematoma showed prostate cancer infiltration. Metastatic disease affecting the outer membrane of the chronic subdural haematoma is an exceptional finding described in only two literature reports so far. This exceptional finding together with literature data about non traumatic chronic subdural haematomas in patients with tumorous involvement of dura mater support the benefit of histological evaluation of the resected membranes of the chronic subdural haematoma in patients without the history of trauma and the necessity of such investigation in patients with cancer history because of tumorous etiology of chronic subdural haematoma.

Keywords: chronic subdural haematoma, prostate cancer, metastasis to chronic subdural hematoma membranes.