Neurológia pre prax 5/2017

Characterization of eating disorder in progressive supranuclear palsy

Progressive supranuclear palsy (PSP) represents an atypical parkinsonian syndrome, presenting with symmetrical parkinsonism, early and progressive postural instability with frequent falls, supranuclear gaze palsy, frontal cognitive disorder and some other symptoms. A poorly levodopa responsivity is typical. In the early course of disease develops an eating disorder, particularly progressive dysphagia, often leading to complications such as aspiration pneumonia, a frequent cause of death. In addition to that, a distinct eating behavior is typical for the disorder, for example difficulty with judging the amount of food, binge eating or recently described greed for food. This short review summarizes the facts about pathogenesis, contributing factors, clinical picture and finally management of eating disorder in PSP.

Keywords: eating disorder, progressive supranuclear palsy, dysphagia, eating behavior