Neurológia pre prax 3/2015

Cerebral amyloid angiopathy

Cerebral amyloid angiopathy is characterized by amyloid deposition in the walls of cortical and leptomeningeal arteries and arterioles. Disorder occurs most frequently as a sporadic form in the elderly. Incidence of sporadic form increases with advancing age. Hereditary forms are earlier in onset. The most important clinical consequence of the disease are recurrent lobar intracerebral hemorrhages. Progressive cognitive impairment and dementia can also be present. In a case report of 76-year-old patient with recurrent intracerebral hemorrhage and dementia authors present current options of diagnostics, prevention and treatment of cerebral amyloid angiopathy.

Keywords: cerebral amyloid angiopathy, recurrent intracerebral hemorrhages, cognitive impairment.