Neurológia pre prax 2/2021

Cerebellar ataxia and stiff person syndrome in patient with anti-GAD antibodies

Anti-GAD-antibody-associated neurological conditions are typically seen in young or middle-aged females and are often associated with other autoimmune disorders. We report a patient with anti-GAD associated ataxia, in whom symptoms of stiff person syndrome (SPS) as well as diabetes mellitus type 1 (IDDM) and hypothyroidism followed 2.5 years after diagnosis.

Keywords: cerebellar ataxia, stiff person syndrome, glutamic acid decarboxylase antibodies, anti-GAD antibodies