Neurológia pre prax 2/2024

Central post-stroke pain

Central Post-Stroke Pain (CPSP) is defined as a painful condition after a central stroke with a proven lesion in the central nervous system (CNS). Clinical signs appear as early as 1-3 months after the stroke, but in most affected patients it is up to 6 months. Major clinical manifestations include tension headache, pain associated with muscle spasticity and pain shoulder syndrome with possible development of complex regional pain syndrome (CRPS). The treatment combines the use of analgesics (amitriptyline, carbamazepine, gabapentinoids), physiotherapy and psychotherapeutic procedures.

Keywords: central post‑stroke pain, central neuropatic pain, spasticity