Neurológia pre prax 6/2012

Early diagnosis of Alzheimer’s disease in the light of new diagnostic criteria

New Alzheimer´s disease (AD) criteria emphasizing early diagnosis with the use of biomarkers have been published in 2011. Besides the revised criteria for dementia due to AD, the new concept of preclinical AD and of Mild cognitive impairment due to AD has been defined. This paper summarizes the principles of diagnosis according to the new criteria and their practical significance. We propose a diagnostic procedure of AD useful in routine clinical practice.

Keywords: Alzheimer’s disease, dementia, mild cognitive impairment, biomarkers, diagnostic criteria.