Neurológia pre prax 3/2022
Autoimmune encephalitis associated with anti-Caspr2 antibodies
We present a case report of a 61-year-old man with an acute onset of epileptic seizures, encephalopathy, delirium, peripheral nerve hyperexcitability syndrome and dysautonomy with indentified anti-Caspr2 antibodies whose clinical status has promptly improved after a high dose of corticosteroids. Subsequently a short review of anti-Caspr2 pathophysiology, spectrum of clinical manifestation with emphasis put on a typical Morvan syndrome, diagnostics and treatment of these conditions is presented.
Keywords: anti-Caspr2, autoimmune encephalitis, Morvan syndrome
