Neurológia pre prax 3/2011

Acute polyradiculoneuritis – differential diagnostics

Acute polyradiculoneuritis is an autoimmune-based neuropathy and represents an important diagnostic and therapeutic problem. In Europe demyelinating forms prevail (more than 80 %), whereas in China and in Middle and Southern America the axonal forms represent more important portion. During diagnosis setting there is necessary to evaluate clinical finding and a course of disease, then laboratory analysis of blood and urine follow, further electrophysiological investigations (motor and sensory neurography, F-waves, H-reflex) and withdrawal of cerebrospinal fluid. During differential diagnostic process there is to evaluate and differentiate a couple of various disoders.

Keywords: acute polyradiculoneuritis, molecular mimicry, demyelination, axonopathy, electrophysiological investigation, proteincytological dissociation.