Dermatológia pre prax 2/2017

Current possibilities of treatment of atopic eczema

Atopic eczema (AE) is a chronic, inflammatory skin disorder. In spite of intensive investigations, the causes of AE remain uncelar, but are likely to be multifactorial in nature. Among various measures of AE managment skin hydration, which improves barrier function and relieve itchiness, may be helpful to reduce the need for topical steroid use and therefore it should be used as a basic treatment. Avoiding aggravating factors is also a basic treatment of AE. Standard medical treatment with a pharmacologic approach may be necessary if basic treatment fails to control symptoms sufficiently. Recently,more attention is given to proactive treatment regimen by regular intermittent application of topical corticosteroids or topical calcineurin inhibitors to prevent new flares. Furthermore, various targeted bilogics are being introduced for AE control and are proposed to represent promising therapies.

Keywords: atopic eczema, reviews of treatments, cleansing and bathing, emollients, topical anti-inflammatory therapy, systemic immunosuppressants, biologics