Dermatológia pre prax 3-4/2007

CONTACT HYPERSENSITIVITY TO MEDICATIONS AFTER EXTERNAL USE

Components of externally used medications may cause contact hypersensitivity. Both active and supportive components may become allergens. Sulphonamides, local anesthetics, antibiotics, antimycotic medications, nonsteroidal anti-inflammatory drugs, and corticosteroids as active substances, and preserving, antioxidant, and emulsifying agents as supportive substances may all trigger contact sensibilization. Currently sensibilization to neomycin, ketoprophen and corticosteroids is the most important.

Keywords: medications for external use, contact hypersensitivity, active substances, supportive substances