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Dermatológia pre prax 3/2009
Comorbidities in psoriasis – a new perspective of an old disease
Psoriasis is multifactorial disease with manifestation on genetic background. The manifestation under provoking factors is the result of many genes. There are some possible associations between psoriasis and comorbid conditions in this way. Psoriasis is driven by immune mechanisms with important role of activated T lymphocytes and some factors of non specific immunity. Inflammation in psoriasis could be connected i. e. with some cardiovascular diseases. Especially in severe psoriasis effective systemic treatment is necessary. Biologicals are hopeful in this way.
Keywords: multigenic background, comorbidities, treatment
