Dermatológia pre prax 3-4/2007
MERKEL CELL CARCINOMA
Merkel Cell Carcinoma (MCC) is a neuroendocrine skin cancer with the agressive biological behaviour. Incidence of MCC is 0,4 per 100 000 and five years survival rate is 65 %. The most common sites of primary lesion are head, neck and extremities. Optimal treatment of patiens with MCC is radical surgery, dissection of regional lymphatic nodes with sentinel lymph node detection and adjuvant locoregional radiotherapy if risk prognostic factors are present. The role of chemotherapy is controversial and should be considered in patients with advanced disease.
Keywords: Merkel Cell Carcinoma, epidemiology, diagnostics, therapy and prognosis
